Two formulations of
Guduchi : Preparation and Organoleptic tests
Dr.Vaidehi Patankar,
Dr. Madhuri Pawar, Dr Swati Gadgil
Guduchi
is one of the “Medhya Rasayan” drug stated in Charak Samhita with its specific
form of administration i.e. “Swaras” [Fresh juice].
Many
previous research works are there with different forms of Guduchi such as
Guduchi Choorna , Kwath or ethanolic and water extractives in which Guduchi
Kanda (stem) is used.
Here
we have used Fresh Guduchi Kanda (Stem), Patra (Leaves) and Moola(Roots)
Identification and Authentication
of Raw Drug
Whole plant of Guduchi
(Tinospora Cordifolia) was used as a Raw Drug.
It was handpicked sample
and identified from botany expert from IRSHA, Pune.
Authentication with
Macroscopic and Microscopic characters of raw drug was done in IDRAL
Laboratory, Pune,
Pharmaceutics of Guduchi
Swaras
In present study Guduchi
Swaras was prepared as per the standard protocol stated in Sharangdhar
Samhita Madhyam Khanda 1st Chapter verse no.2.
आहतात्
तत्क्षणाकृष्टात् द्रव्यात् क्षुण्णात् समुद्धरेत् I
वस्त्र निष्पिडितो
यः सः रसः स्वरसः उच्यते II
1. Manufacturing of Guduchi
Swaras
2. Analysis of Guduchi
Swaras
Method:
Identified and
Authenticated Guduchi Whole plant was handpicked from authentic source.
Guduchi
Stem having bitter taste was selected for study.Heart shaped green leaf and
fresh roots were collected from same plant source.
Preparation of Guduchi
swaras:
Standard Operating
Procedures were carried out throughout the process.
Ingredients of Gududhci
Swaras :’
|
Sr.No
.
|
Material Used
|
Part Used
|
Quantity
|
|
1.
|
Guduchi (Tinospora cordifolia)
|
Whole plant
(Total)
|
5000gms
|
|
1.1
|
Guduchi stem
|
Kanda
|
3500 gms
|
|
1.2
|
Guduchi leaves
|
Patra
|
1000 gms
|
|
1.3
|
Guduchi roots
|
Moola
|
500 gms
|
|
2.
|
Water
|
-
|
1200mL
|
Instruments:
Mortar-Pestle, Wet
Grinder, Measuring cylinder, Iron Vessel, Spoon, Muslin Cloth, Gas Stove
Procedure:
·
Cleaning: Whole plant
of Guduchi were separated as Stem, Roots and Leaves and weighed individually.
An Individual collected part of plants were washed under running tap water for
3 times.
·
Grinding: The washed
stem, small roots and leaves were cut into small pieces and pounded over stony mortar-Pestle.
The pounded mixture was put into wet grinder with 25% of water to have moderate
rough paste.
·
Filtering:
Obtained
rough paste was taken into a clean muslin cloth and tied tightly and it was
squeezed to have Guduchi Swaras. It was then measured with measuring cylinder.
·
In process and final
testing was done as per the ayurvedic parameters further Guduchi Swaras was
analyzed with API parameters.
Preparation of Guduchi Kalpa:
For better palatability
and to increase shelf life of Guduchi swaras “Kalpa” was formulated. It was
prepared as per the standard protocol stated for avaleha in Sharangdhar Samhita Madhyam Khanda 8th
chapter verse No.1 as “ Kalpa is to be consider as an advance form of “Avaleha
Form”
क्वाथादिनां पुनः
पाकाद्घनत्वं सा रसक्रिया I
सोsवलेहश्च लेहः स्यात् तस्य मात्रा पलोन्मिता II
Table for Quantity of Raw drug
|
Sr.No
|
Raw
Drug used
|
Quantity
|
Time
required to manufacture
|
|
1.
|
Guduchi
swaras
|
350mL
|
45
Min
|
|
2.
|
Sita
(Sugar)
|
700
gms
|
ORGNAOLEPTIC
CHARACTERISTICS OF GUDUCHI SWARAS
|
ORGANOLEPTIC
TEST
|
||
|
Sr.No.
|
Parameters
|
Observations
|
|
1.
|
Shabda
|
-
|
|
2.
|
Sparsha
|
Picchila
|
|
3.
|
Roopa
|
Dark
Green colour
|
|
4.
|
Rasa
|
Tikta
|
|
5.
|
Gandha
|
Ugra Gandhi
|
ORGNAOLEPTIC
CHARACTERISTICS OF GUDUCHI KALPA
|
ORGANOLEPTIC
TEST
|
||
|
Sr.No.
|
Parameters
|
Observations
|
|
1.
|
Shabda
|
Not
applicable
|
|
2.
|
Sparsha
|
Khar-Sushka
|
|
3.
|
Roopa
|
Cream colour
|
|
4.
|
Rasa
|
Madhur-Tikta
|
|
5.
|
Gandha
|
Sugandhi
|
Interpretation:
Handpicked sample of Fresh Guduchi [Tinospora cordifolia] identified and
authenticated
Two dosage forms of Guduchi prepared as per standard ayurvedic protocols
Standard operating procedures for Guduchi Swaras and Kalpa are developed.
Organoleptic characteristics of both formulations are estimated
