Title:
Pharmaceutical standardization of VachadiGhrita
with laboratory methods
Sonune A., Gurav K., Wele A., Pawar M.
Department of RSBKV, BVDUCOA, Pune.
Abstract:
Vachadighrita[VG]
is a known formulation having action on CNS. Ingredients of VG are paste of Vacha [Acorus calamus], Guduchi [Tinospora cordifolia], Shati [Hedychium spicatum], Shankhapushpi [Convolvulus pluricaulis],
Haritaki [Terminalia chebula], Vidang [Embelia ribes], Shunthi [Zingiber officinale], Apamarg [Achyranthes aspera], cow ghee
and water.This study is based on innovation in manufacturing process in
comparison with traditional guidelines. SOP for manufacture of medicated ghee
was followed throughout the processandVG was prepared by heating ghee, herbal
drug paste and water together.Three samples of VG were prepared by 3 different
ways, i.e. VG1using fine powder, VG2 with coarse powder and VG3with mixture of
fine and coarse powder of herbal drugs.Fourth batch [VG4]was prepared by using paste
of fine powder and addition of sodium bicarbonate. The use of sodium
bicarbonate was experimented as an innovation. The final weight was maximum i.e.
92 % in VG4, 80 % in VG2 and 70 % inVG3. It was minimum i.e. 50% in VG1. Maximum
bitterness and strong odour was found inVG4 sample with least % weight loss. Hence
it is evident that the innovation of addition of sodium bicarbonate and use of
fine pasteproduced medicated ghee of best strength. Further VG4 was analyzed
with API parameters.Thus study established the innovatory manufacture process
and analytical values of Vachadighrita.
